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Multidrug-resistant tuberculosis: a comprehensive review of pathogenesis, drug resistance, current treatment and future prospects.

Archives of microbiology - 19 May 2026

Tiwari Shweta, Singh Ankit Kumar, Acharya Aarshu, Ghosh Joyabroto, Singh Rashmi Prabha

Abstract excerpt

Tuberculosis (TB) accounted for almost 1.2 million deaths in 2024. It remains a leading cause of mortality due to an airborne infectious bacterium, Mycobacterium tuberculosis (MTB). Despite the development of vaccines and antibiotics to cure the disease, it remains a major global problem due to the development of several ingenious pathogenic pathways. This comprehensive review introduces the mechanisms of...

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PMID: 42154079
DOI: 10.1007/s00203-026-04938-y

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