Article

A chemical-genetic map of the pathways controlling drug potency in <i>Mycobacterium tuberculosis</i>

2021-11-27

Abstract excerpt

<h4>ABSTRACT</h4> Mycobacterium tuberculosis (Mtb) infection is notoriously difficult to treat. Treatment efficacy is limited by Mtb’s intrinsic drug resistance, as well as its ability to evolve acquired resistance to all antituberculars in clinical use. A deeper understanding of the bacterial pathways that govern drug efficacy could facilitate the development of more effective therapies to overcome resistance, i...

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Literature Corpus work: c986dc61-834c-541a-b4f0-270c217b5cad
DOI: 10.1101/2021.11.27.469863

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