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Article

TEAD1 is a novel regulator of NRF2 and oxidative stress response in cardiomyocytes

2025-04-06

Abstract excerpt

<h4>ABSTRACT</h4> <h4>BACKGROUND</h4> TEAD1, the mammalian Hippo pathway-regulated transcription factor, plays a critical and non-redundant role in maintaining cardiomyocyte (CM) homeostasis. However, the specific cellular pathways regulated by TEAD1 in CMs remain poorly defined. We hypothesized that TEAD1 has an essential, cell-autonomous role in the CM oxidative stress response by directly regulating the trans...

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Identifiers and source

Literature Corpus work
74f9b255-bca5-577b-a3af-61e12927a398
DOI
10.1101/2025.04.06.647438
Open publication

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TEAD1 is a novel regulator of NRF2 and oxidative stress response in cardiomyocytesDOI 10.1101/2025.04.06.647438
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