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Article

Molecular Mechanisms of Cardiomyocyte Aging

2025-08-01

Abstract excerpt

Aging is a major risk factor for cardiovascular diseases, yet the underlying molecular mechanisms remain poorly understood. In this study, we integrated physiological characterization of cardiomyocyte (CM) aging with concurrent single-nucleus RNA-seq and ATAC-seq, and reduced representation bisulfite sequencing to delineate the cellular and molecular landscape of CM aging in mice. Our analysis revealed significant...

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Literature Corpus work
d0053fe2-82ca-5863-8bf3-d2091a6dbf85
DOI
10.1101/2025.07.29.666777
Open publication

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Molecular Mechanisms of Cardiomyocyte AgingDOI 10.1101/2025.07.29.666777
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