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The Dark Side of Nrf2 in the Heart

9 Jul 2020

Abstract excerpt

Nuclear factor-erythroid factor 2-related factor 2 (Nrf2) is a critical transcription factor that regulates the expression of over 1000 genes in the cell under normal and stressed conditions. These transcripts can be categorized into different groups with distinct functions, including antioxidative defense, detoxification, inflammatory responses, transcription factors, proteasomal and autophagic degradation, and...

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PMID: 32733266
DOI: 10.3389/fphys.2020.00722

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