Article

Exapted CRISPR-Cas12f homologs drive RNA-guided transcription

2025-06-10

Abstract excerpt

<h4>ABSTRACT</h4> Bacterial transcription initiation is a tightly regulated process that canonically relies on sequence-specific promoter recognition by dedicated sigma (σ) factors, leading to functional DNA engagement by RNA polymerase (RNAP) 1 . Although the seven σ factors in E. coli have been extensively characterized 2 , Bacteroidetes species encode dozens of specialized, extracytoplasmic function σ facto...

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Literature Corpus work: 74d9cbcd-58d9-54f0-a24a-acdb1edfdc86
DOI: 10.1101/2025.06.10.658865

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