Article
CRISPR-Cas tools for simultaneous transcription & translation control in bacteria
2023-10-12
Abstract excerpt
Robust control over gene translation at arbitrary mRNA targets is an outstanding challenge in microbial synthetic biology. The development of tools that can regulate translation will greatly expand our ability to precisely control genes across the genome. In E. coli , most genes are contained in multi-gene operons, which are subject to polar effects where targeting one gene for repression leads to silencing of bo...
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Identifiers and source
- Literature Corpus work
- 10ca1984-c90f-5d45-8fa7-f1d5903755f8
- DOI
- 10.1101/2023.10.11.561958