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Article

Programmable and portable CRISPR-Cas transcriptional activation in bacteria

2020-01-03

Abstract excerpt

<h4>ABSTRACT</h4> Programmable gene activation enables fine-tuned regulation of endogenous and synthetic gene circuits to control cellular behavior. While CRISPR-Cas-mediated gene activation have been extensively developed for eukaryotic systems, similar strategies have been difficult to implement in bacteria. Here, we present a generalizable platform for screening and selection of functional bacterial CRISPR-Cas...

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Literature Corpus work
54a8eaa6-9c01-59d6-afbf-2cf65ff279f7
DOI
10.1101/2020.01.03.882431
Open publication

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Programmable and portable CRISPR-Cas transcriptional activation in bacteriaDOI 10.1101/2020.01.03.882431
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