Article

A Gene Based Optimally Weighted Combination Test Using GWAS Summary Data

2022-06-29

Abstract excerpt

<h4>Background: </h4> Gene-based association tests provide a useful alternative and complement to the usual single marker association tests, especially in genome-wide association studies (GWAS). The way of weighting for variants in a gene plays an important role in boosting the power of a gene-based association test. Appropriate weights can boost statistical power, especially when detecting genetic variants with w...

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Literature Corpus work: 744c0394-9bd8-5a64-b5a9-eba6c73a4ecf
DOI: 10.21203/rs.3.rs-1720857/v1

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