Article

A General Statistic to Test an Optimally Weighted Combination of Common and/or Rare Variants

2019-03-09

Abstract excerpt

Both genome-wide association study and next generation sequencing data analyses are widely employed in order to identify disease susceptible common and/or rare genetic variants in many large scale genetic studies. Rare variants generally have large effects though they are hard to detect due to their low frequency. Currently, many existing statistical methods for rare variants association studies employ a weighted...

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Literature Corpus work: 78805ba1-7827-5261-920c-481abc8a158f
DOI: 10.1101/572115

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