Back to search

Article

Testing an Optimally Weighted Combination of Common and/or Rare Variants with Multiple Traits

2018-03-14

Abstract excerpt

Joint analysis of multiple traits has recently become popular since it can increase statistical power to detect genetic variants and there is increasing evidence showing that pleiotropy is a widespread phenomenon in complex diseases. Currently, most of existing methods test the association between multiple traits and a single common variant. However, the variant-by-variant methods for common variant association st...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
cb8284c5-3bac-5a91-bcd3-2de3cee6a403
DOI
10.1101/281832
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Testing an Optimally Weighted Combination of Common and/or Rare Variants with Multiple TraitsDOI 10.1101/281832
Select a neighboring publication to make it the new centre.