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Powerful statistical method to detect disease associated genes using publicly available GWAS summary data

2018-11-25

Abstract excerpt

Genome-wide association studies (GWAS) have thus far achieved substantial success. In the last decade a large number of common variants underlying complex diseases have been identified through GWAS. In most existing GWAS, the identified common variants are obtained by single marker based tests, that is, testing one single nucleotide polymorphisms (SNP) at a time. Generally the basic functional unit of inheritance...

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Literature Corpus work
cb70f040-f54b-52cc-a186-02fef7bab3a3
DOI
10.1101/478321
Open publication

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Powerful statistical method to detect disease associated genes using publicly available GWAS summary dataDOI 10.1101/478321
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