Article
Leveraging existing GWAS summary data of genetically correlated and uncorrelated traits to improve power for a new GWAS.
Genetic epidemiology - 1 Oct 2020
Xue Haoran, Wu Chong, Pan Wei
Abstract excerpt
In spite of the tremendous success of genome-wide association studies (GWAS) in identifying genetic variants associated with complex traits and common diseases, many more are yet to be discovered. Hence, it is always desirable to improve the statistical power of GWAS. Paralleling with the intensive efforts of integrating GWAS with functional annotations or other omic data, we propose leveraging other published...
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