Article

A gene based approach to test genetic association based on an Optimally Weighted Combination of Multiple Traits

2019-03-28

Abstract excerpt

There is increasing evidence showing that pleiotropy is a widespread phenomenon in complex diseases for which multiple correlated traits are often measured. Joint analysis of multiple traits could increase statistical power by aggregating multiple weak effects. Existing methods for multiple trait association tests usually study each of the multiple traits separately and then combine the univariate test statistics...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 81e5dd56-fc75-56ac-bb78-fc294c2a3152
DOI: 10.1101/592568

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

A gene based approach to test genetic association based on an Optimally Weighted Combination of Multiple TraitsDOI 10.1101/592568Read

Testing an optimally weighted combination of common and/or rare variants with multiple traits.Semantic proximity Read

Testing an Optimally Weighted Combination of Common and/or Rare Variants with Multiple TraitsSemantic proximity Read

A novel method to test associations between a weighted combination of phenotypes and genetic variants.Semantic proximity Read

A Gene Based Optimally Weighted Combination Test Using GWAS Summary DataSemantic proximity Read

Detecting association of rare and common variants by testing an optimally weighted combination of variants.Semantic proximity Read

Test Gene-Environment Interactions for Multiple Traits in Sequencing Association StudiesSemantic proximity Read

Gene- and pathway-based association tests for multiple traits with GWAS summary statistics.Semantic proximity Read

Testing gene-environment interactions for rare and/or common variants in sequencing association studiesSemantic proximity Read

Integrating Multiple Correlated Phenotypes for Genetic Association Analysis by Maximizing Heritability.Semantic proximity Read

Testing gene-environment interactions for rare and/or common variants in sequencing association studies.Semantic proximity Read

Analysis of multiple related phenotypes in genome-wide association studies.Semantic proximity Read

MF-TOWmuT: Testing an optimally weighted combination of common and rare variants with multiple traits using family data.Semantic proximity Read