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Article

Testing an optimally weighted combination of common and/or rare variants with multiple traits.

PloS one - 1 Jan 2018

Wang Zhenchuan, Sha Qiuying, Fang Shurong, Zhang Kui, Zhang Shuanglin

Abstract excerpt

Recently, joint analysis of multiple traits has become popular because it can increase statistical power to identify genetic variants associated with complex diseases. In addition, there is increasing evidence indicating that pleiotropy is a widespread phenomenon in complex diseases. Currently, most of existing methods test the association between multiple traits and a single genetic variant. However, these...

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PMID: 30048520
DOI: 10.1371/journal.pone.0201186
PMCID: PMC6062080

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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