Article

Human pluripotent stem cell-derived brain pericyte-like cells induce blood-brain barrier properties

2018-08-07

Abstract excerpt

<h4>ABSTRACT</h4> Brain pericytes play an important role in the formation and maintenance of the neurovascular unit (NVU), and their dysfunction has been implicated in central nervous system (CNS) disorders. While human pluripotent stem cells (hPSCs) have been used to model other components of the NVU including brain microvascular endothelial cells (BMECs), astrocytes, and neurons, cells having brain pericyte-lik...

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Literature Corpus work: 715bf466-2907-5baf-a2c6-e4a5b71d8681
DOI: 10.1101/387100

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