Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Differentiation of Human Induced Pluripotent Stem Cells to Brain Microvascular Endothelial Cell-Like Cells with a Mature Immune Phenotype.

Journal of visualized experiments : JoVE - 19 May 2023

Matsuo Kinya, Engelhardt Britta, Nishihara Hideaki

Abstract excerpt

Blood-brain barrier (BBB) dysfunction is a pathological hallmark of many neurodegenerative and neuroinflammatory diseases affecting the central nervous system (CNS). Due to the limited access to disease-related BBB samples, it is still not well understood whether BBB malfunction is causative for disease development or rather a consequence of the neuroinflammatory or neurodegenerative process. Human induced...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blood-Brain Barrier
Share to Brain

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Differentiation

Share to Cells, Cultured

Share to Endothelial Cells

Share to Induced Pluripotent Stem Cells

Share to Phenotype

Source

Identifiers

PMID: 37318257
DOI: 10.3791/65134

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Differentiation of Human Induced Pluripotent Stem Cells to Brain Microvascular Endothelial Cell-Like Cells with a Mature Immune Phenotype.PMID 37318257Read ↗

Directed differentiation of human pluripotent stem cells to blood-brain barrier endothelial cells.Semantic proximity Read ↗

Pericytes and Wnt signaling induce functional blood-brain barrier phenotype in human iPSC-based modelSemantic proximity Read ↗

Human induced pluripotent stem cell-derived neuroectodermal epithelial cells mistaken for blood-brain barrier-forming endothelial cellsSemantic proximity Read ↗

Derivation of blood-brain barrier endothelial cells from human pluripotent stem cells.Semantic proximity Read ↗

Brain Pericytes and Wnt/β-Catenin Signaling Induce Functional Blood-Brain Barrier Phenotype in Human iPSC-Derived Model.Semantic proximity Read ↗

Generation of hiPSC-derived brain microvascular endothelial cells using a combination of directed differentiation and transcriptional reprogramming strategiesSemantic proximity Read ↗

High and low permeability of human pluripotent stem cell-derived Blood Brain barrier models depend on epithelial or endothelial featuresSemantic proximity Read ↗

Wnt signaling mediates acquisition of blood-brain barrier properties in naïve endothelium derived from human pluripotent stem cellsSemantic proximity Read ↗

Human pluripotent stem cell-derived brain pericyte-like cells induce blood-brain barrier propertiesSemantic proximity Read ↗

Vascularized Brain Assembloids with Enhanced Cellular Complexity Provide Insights into The Cellular Deficits of TauopathySemantic proximity Read ↗

Combinatorial Modulation of Wnt, STAT3, TGF-β, and Tie2 Pathways Drives Brain Endothelial Cell-Like Differentiation from hiPSCsSemantic proximity Read ↗

Schizophrenia-derived hiPSC brain microvascular endothelial cells show impairments in angiogenesis and blood-brain barrier functionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.