Article

Induced pluripotent stem cell derived pericytes respond to endogenous mediators of proliferation and contractility

2023-10-01

Abstract excerpt

<h4>Background</h4> Pericytes are multifunctional contractile cells that reside on capillaries. Pericytes are critical regulators of cerebral blood flow and blood-brain barrier function, and pericyte dysfunction may contribute to the pathophysiology of human neurological diseases including Alzheimers disease, multiple sclerosis, and stroke. Induced pluripotent stem cell (iPSC)-derived pericytes (iPericytes) are a...

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Literature Corpus work: 8c205564-1437-5a71-925e-0a0c3102170e
DOI: 10.1101/2023.09.29.560066

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