Article

3D organoids containing endothelial and neural cells generation by serial inductions of differentiation on human iPSC-derived embryoid bodies

2025-05-21

Abstract excerpt

3D brain organoids have been widely used as a tool to study human brain development and disorders. Although endothelial cells play important roles in the brain development and pathogenesis in neurological disorders, most 3D brain organoids lack inherent endothelial cells and need either the addition of endothelial cells or to be transplanted to animals to reconstitute such vascular structures, likely missing the d...

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Literature Corpus work: 1eb8bf07-edf1-5373-9248-af0dce5f9fa4
DOI: 10.1101/2025.05.20.653559

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