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A novel human blood-brain barrier model reveals pericytes as critical regulators of viral neuroinvasion

2025-01-03

Abstract excerpt

The blood-brain barrier (BBB) plays a vital role in regulating the passage of biomolecules between the bloodstream and the central nervous system (CNS) while also protecting the CNS from pathogens. Pericytes reside at the interface between the endothelial cells that form the vessel walls and the brain parenchyma. These cells are critical for maintaining BBB integrity and play key roles in regulating vessel permeab...

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Identifiers and source

Literature Corpus work
7846a732-37c7-541a-b40c-6749b2c6c1fa
DOI
10.1101/2024.12.18.629173
Open publication

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