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Article

Conserved cell-type specific signature of resilience to Alzheimer’s disease nominates role for excitatory intratelencephalic cortical neurons

2022-04-13

Abstract excerpt

<h4>Summary</h4> Alzheimer’s disease (AD), the leading cause of dementia, affects millions of people worldwide. With no disease-modifying medication currently available, the human toll and economic costs are rising rapidly. Under current standards, a patient is diagnosed with AD when both cognitive decline and pathology (amyloid plaques and neurofibrillary tangles) are present. Remarkably, some individuals who ha...

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Literature Corpus work
70a23879-2aa0-508f-b6a6-e8a9aa729b36
DOI
10.1101/2022.04.12.487877
Open publication

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Conserved cell-type specific signature of resilience to Alzheimer’s disease nominates role for excitatory intratelencephalic cortical neuronsDOI 10.1101/2022.04.12.487877
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