Article

Robust genome editing via modRNA-based Cas9 or base editor in human pluripotent stem cells

2022-05-24

Abstract excerpt

<h4>Summary</h4> CRISPR systems have revolutionized biomedical research because they offer an unprecedented opportunity to explore the application of genome editing in human pluripotent stem cells (hPSCs). Due to the inherent simplicity of CRISPR systems, requiring a Cas protein and its corresponding single guide RNA (sgRNA), they are more widely adopted and used for diverse biomedical research than their predece...

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Literature Corpus work: 6fe1f4ec-8599-53c8-b034-c993aec6d573
DOI: 10.1101/2022.05.24.493220

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