Article

Sensory neurons inhibit invadopodia and metastasis via direct CGRP-RAMP1-cAMP signaling to cancer cells

2026-04-21

Abstract excerpt

Breast cancer is globally the most common cancer among women. Although the five-year survival rate exceeds 80% for patients with localized disease, it drops to approximately 30% once metastasis occurs, underscoring the urgent need to define mechanisms that drive metastatic progression. Breast is a highly innervated organ and most of its innervation is sensory. However, whether sensory neurons can directly impact b...

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Literature Corpus work: 6e1f5e6e-3590-5c22-915c-7bf52e508a33
DOI: 10.64898/2026.04.17.719233

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