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Opioid-expressing B Cells Silence Tumor-infiltrating Nociceptor Neurons

2025-09-03

Abstract excerpt

<title>Abstract</title> <p>Nociceptor neurons, which transmit pain signals, also regulate immunity by releasing immunomodulatory neuropeptides. In head and neck squamous cell carcinoma (HNSCC) and melanoma, our research has shown that tumor-innervating nociceptors modulate anti-tumor immunity through the release of calcitonin gene-related peptide (CGRP) and its interaction with receptor activity-modifying protein...

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Literature Corpus work
1c6bcb9f-ce9f-5d27-a18c-6378e18e320e
DOI
10.21203/rs.3.rs-7389517/v1
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Opioid-expressing B Cells Silence Tumor-infiltrating Nociceptor NeuronsDOI 10.21203/rs.3.rs-7389517/v1
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