Article

Expression of neuronal Na+ leak channel, NALCN, provides for persistent invasion of metastasizing cancer cells

2020-08-13

Abstract excerpt

Cytosolic Ca2+ oscillations provide signaling input to several effector systems of the cell. These include neuronal development, migration and networking. Although similar signaling events are hijacked by highly aggressive cancer cells, the complexity of the ‘neuron-like’ remodeling in metastasis remains to be explored. Here, using a variety of in vitro and in vivo techniques we show that strongly metastatic prost...

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Literature Corpus work: d2c668c4-9df7-5a20-9c16-53c4c1da3483
DOI: 10.1101/2020.08.13.249169

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