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Article

Identification of subsets of actionable genetic alterations in KRAS-mutant lung cancers using association rule mining.

Cellular oncology (Dordrecht, Netherlands) - 1 Aug 2018

Tayou Junior

Abstract excerpt

BACKGROUND: Lung cancer is the leading cause of cancer-related death in both men and women. KRAS mutations occur in ~ 25% of patients with lung cancer, and the presence of these mutations is associated with a poor prognosis. Unfortunately, efforts to directly target KRAS or its associated downstream MAPK or PI3K/AKT/mTOR pathways have seen little or no benefits. Here, I hypothesize that KRAS-mutant tumors do not...

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Source

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Identifiers

PMID: 29679238
DOI: 10.1007/s13402-018-0377-5
PMCID: PMC12995247

Genes

KRAS
STAT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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