Article
The Abundance of KRAS and RAS Gene Mutations in Cancer.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2024
Stites Edward C
Abstract excerpt
Mutant forms of the RAS genes KRAS, NRAS, and HRAS are important and common drivers of cancer. Recently, two independent teams that integrated cancer genomics with cancer epidemiology estimated that approximately 15-20% of all human cancers harbor a mutation in one of these three RAS genes. These groups also estimate KRAS mutations occur in 11-14% of all human cancers. Although these estimates are lower than many...
Topics
- Humans
- Genes, ras
- Proto-Oncogene Proteins p21(ras)
- ras Proteins
- Neoplasms
- Mutation