Article

Characterising the contribution of rare protein-coding germline variants to prostate cancer risk and severity in 37,184 cases

2024-05-10

Abstract excerpt

The etiology of prostate cancer, the second most common cancer in men globally, has a strong heritable component. While rare coding germline variants in several genes have been identified as risk factors from candidate gene and linkage studies, the exome-wide spectrum of causal rare variants remains to be fully explored. To more comprehensively address their contribution, we analysed data from 37,184 prostate canc...

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Literature Corpus work: 6bdc47be-67a9-5583-a7b8-0504e4aa561e
DOI: 10.1101/2024.05.10.24307164

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