Article

Association Study of Over 200,000 Subjects Detects Novel Rare Variants, Functional Elements, and Polygenic Architecture of Prostate Cancer Susceptibility

2020-02-12

Abstract excerpt

<h4>ABSTRACT</h4> The potential association between rare germline genetic variants and prostate cancer (PrCa) susceptibility has been understudied due to challenges with assessing rare variation. Furthermore, although common risk variants for PrCa have shown limited individual effect sizes, their cumulative effect may be of similar magnitude as high penetrance mutations. To identify rare variants associated with...

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Literature Corpus work: b2bdd093-c598-538b-8537-881eeed7e983
DOI: 10.1101/2020.02.12.929463

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