Article
Inherited Predisposition to Prostate Cancer: From Gene Discovery to Clinical Impact.
Transactions of the American Clinical and Climatological Association - 1 Jan 2017
Cooney Kathleen A
Abstract excerpt
Family history of prostate cancer is one of the three most important risk factors for the disease in addition to age and race. Yet despite the recognition of this significant heritable component, it has been challenging to identify the genes associated with prostate cancer predisposition. Initial approaches focused on the collection of multiplex prostate cancer families. However, despite more than 20 years of...
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