Article
Expression reduction of biallelically transcribed X-linked genes during the human female preimplantation development
2019-06-27
Abstract excerpt
Our previous single-cell RNA-seq data from human preimplantation embryos showed that female X-chromosome mRNA levels become partly dose compensated during the timespan between zygotic genome activation (ZGA) and implantation. At the same time, XIST RNA is expressed from, and forms clouds in proximity to, both X-chromosome copies and biallelic expression of other X-linked genes persists. We proposed that X-chromos...
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Identifiers and source
- Literature Corpus work
- 6a695a2e-a31e-5011-a8a9-d44f87c1a2ac
- DOI
- 10.1101/682286