Article

Breast cancer polygenic risk score performance varies by socioeconomic status

2026-06-04

Abstract excerpt

<h4>Background</h4> Polygenic risk scores (PRS) for breast cancer are increasingly used for risk stratification to inform screening and prevention. However, for PRSs to be equitable and clinically useful, they need to perform well across diverse populations. While PRS performance is known to be ancestry-dependent, it is not well understood how environmental context, such as that of socioeconomic status (SES), aff...

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Literature Corpus work: 6a27a3f0-b2ba-59b3-a930-24e5d93fbbc9
DOI: 10.64898/2026.06.03.26354819

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