Article

Ancestry-specific polygenic risk scores improve clinical assessments of breast cancer risk in diverse populations

2024-03-18

Abstract excerpt

<title>Abstract</title> <p>A woman’s risk of breast cancer risk can be assessed through models that integrate physiological, environmental and genetic factors. Here we use genome-wide data from 309,479 women including 128,771 with clinical data to build and validate ancestry-specific polygenic risk scores (PRS) for breast cancer (BC) and use them to explore the interplay between clinical factors and rare and comm...

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Literature Corpus work: 6b996456-78e2-5f63-8abe-6b0695fca68f
DOI: 10.21203/rs.3.rs-4022359/v1

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