Article

Performance of polygenic risk scores for cancer prediction in a racially diverse academic biobank

2021-05-19

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Purpose</h4> Genome-wide association studies (GWAS) have identified hundreds of single nucleotide polymorphisms (SNPs) significantly associated with several cancers, but the predictive ability of polygenic risk scores (PRS) is unclear, especially among non-Whites. <h4>Methods</h4> Genome-wide genotype data was available for 20,079 individuals enrolled in an academic biobank. PRS were derived...

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Literature Corpus work: 0c730eab-01cf-57e0-9cee-06a1a840d94f
DOI: 10.1101/2021.05.13.21256833

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