Article

The impact of polygenic score and socioeconomic status in predicting risk for 19 complex diseases

2025-09-04

Abstract excerpt

Both socioeconomic circumstances and genetic predisposition shape disease risk, yet their joint contribution across diseases has not been systematically examined. We studied 19 high-burden diseases in 743,194 participants (729,928 European; 13,266 non-European ancestry) from FinnGen, the UK Biobank, and Generation Scotland. Higher educational attainment was associated with lower risk of most conditions, but with h...

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Literature Corpus work: 308aef5b-29f3-5e49-bf0d-797f1f540134
DOI: 10.1101/2025.09.02.25334913

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