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Article

Polygenic risk scores and breast cancer risk prediction.

Breast (Edinburgh, Scotland) - 1 Feb 2023

Roberts Eleanor, Howell Sacha, Evans D Gareth

Abstract excerpt

Polygenic Risk Scores (PRS) are a major component of accurate breast cancer risk prediction and have the potential to improve screening and prevention strategies. PRS combine the risk from Single nucleotide polymorphisms (SNPs) associated with breast cancer in Genome Wide Association Studies (GWAS) and explain over 30% of breast cancer heritability. When incorporated into risk models, the more personalised risk...

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Identifiers

PMID: 36646003
DOI: 10.1016/j.breast.2023.01.003
PMCID: PMC9982311

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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