Article

Prospective Evaluation of a Breast Cancer Risk Model Integrating Classical Risk Factors and Polygenic Risk in 15 Cohorts from Six Countries

2019-11-05

Abstract excerpt

<h4>ABSTRACT</h4> <h4>PURPOSE</h4> Risk-stratified breast cancer prevention requires accurate identification of women at sufficiently different levels of risk. We conducted a comprehensive evaluation of a model integrating classical risk factors and a recently developed 313-variant polygenic risk score (PRS) to predict breast cancer risk. <h4>METHODS</h4> Fifteen prospective cohorts from six countries with 237,632...

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Literature Corpus work: bf73c19b-bbaf-5621-a0d6-6c97e345740b
DOI: 10.1101/19011171

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