Article

A Breast Cancer Polygenic Risk Score Validation in 15,490 Brazilians using Exome Sequencing

2024-04-22

Abstract excerpt

<h4>Background</h4> Brazil has a highly admixed population. Polygenic Risk Scores (PRS) have mostly been developed from European population studies, and their application to other populations is challenging. To assess the use of PRS for breast cancer (BC) risk in Brazil, we evaluated four PRSs in the Brazilian population. <h4>Methods</h4> We analyzed a Brazilian cohort composed of 6,206 women with a history of bre...

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Literature Corpus work: d7ea38be-a29c-5115-b811-c485f3ac7246
DOI: 10.1101/2024.04.21.24306089

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