Article

Type I IFN promotes pathogenic inflammatory monocyte maturation during H5N1 infection

2022-01-11

Abstract excerpt

Ly6C hi inflammatory monocytes show high IFN responses, and contribute to both protective and pathogenic functions following influenza virus infection. In order to understand the significance of IFN responses in this subset, we examined monocytes during infection with a lethal H5N1 virus that induces high levels of IFN and a low-pathogenicity H1N1 virus that induces low levels of IFN. We show that H5N1 infection...

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Literature Corpus work: 6939a3bf-56a7-53c9-aed4-7de49067571b
DOI: 10.1101/2022.01.10.475751

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