Article

TYPE I INTERFERON-DEPENDENT CELLULAR REMODELING DURING ACUTE PULMONARY MHV INFECTION

2022-02-01

Abstract excerpt

<h4>ABSTRACT</h4> Impaired type I interferon (IFN) responses are predictive of severe disease during pulmonary coronavirus infection. In the periphery, dampened IFN-responsiveness is associated with viremia and hypercytokinemia, however the resolution of IFN-dependent innate immune responses in the lungs remains limited. Here, we aimed to elucidate the early dynamics of antiviral immunity and define the IFN-depen...

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Literature Corpus work: d64bfb43-8012-584b-a604-1b0d57cbe275
DOI: 10.1101/2022.02.01.478627

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