Article

Virus-associated Inflammation Imprints an Inflammatory Profile on Long-lived Monocyte-derived Macrophages in the Human Liver

2024-01-31

Abstract excerpt

Chronic liver injury triggers the activation and recruitment of immune cells, causing antigen-independent tissue damage and liver disease progression. Tissue inflammation can reshape macrophage composition through monocyte replacement. Replacement of tissue macrophages with monocytes differentiating in an inflammatory environment can potentially imprint a phenotype that switches the liver from an immunotolerant or...

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Literature Corpus work: 3e0b7632-144a-5649-ba0f-c1c70b7033bf
DOI: 10.1101/2024.01.31.578178

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Virus-associated Inflammation Imprints an Inflammatory Profile on Long-lived Monocyte-derived Macrophages in the Human LiverDOI 10.1101/2024.01.31.578178Read

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