Article

CCR2-dependent monocyte-derived cells restrict SARS-CoV-2 infection

2021-05-04

Abstract excerpt

SARS-CoV-2 has caused a historic pandemic of respiratory disease (COVID-19) and current evidence suggests severe disease is associated with dysregulated immunity within the respiratory tract. However, the innate immune mechanisms that mediate protection during COVID-19 are not well defined. Here we characterize a mouse model of SARS-CoV-2 infection and find that early CCR2-dependent infiltration of monocytes restr...

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Literature Corpus work: 5b82eb9b-2cd0-51b4-ad01-0ec7019737c7
DOI: 10.1101/2021.05.03.442538

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