Article

Heterogeneity of monocyte subsets and susceptibility to influenza virus contribute to inter-population variability of protective immunity

2020-12-07

Abstract excerpt

There is considerable inter-individual and inter-population variability in response to viruses. The potential of monocytes to elicit type-I interferon responses has attracted attention to their role in viral infections. Here, we use an ex vivo model to characterize the role of cellular heterogeneity in human variation of monocyte responses to influenza A virus (IAV) exposure. Using single-cell RNA-sequencing, we...

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Literature Corpus work: ef82997e-6da8-5b7d-b353-7fccd91fe4e0
DOI: 10.1101/2020.12.07.414151

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