Article

Type I IFN Dynamics Define an Early Checkpoint for Survival and Orchestrate Systemic Neutrophil Heterogeneity in Lethal Viral Infection

2026-01-24

Abstract excerpt

<h4>ABSTRACT</h4> The early host response is critical for protection against viral infections, yet the systemic events that dictate individual differences in outcomes remain poorly defined. Here, we leveraged variability in survival following intranasal vesicular stomatitis virus (VSV) challenge in genetically identical mice to retrospectively profile systemic immune responses associated with survival or lethalit...

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Literature Corpus work: 4343c154-5389-5682-9e71-1a500fee9376
DOI: 10.64898/2026.01.22.701212

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