Article

Influenza-induced activation of recruited alveolar macrophages during the early inflammatory phase drives lung injury and lethality

2020-06-09

Abstract excerpt

Severe respiratory virus infections initiate a robust host immune response that contributes to disease severity. Immunomodulatory strategies that limit virus-initiated inflammation are of critical importance. In this study, we compared the host response to influenza A virus (IAV) infection in susceptible animals (wild-type, WT) to resilient mice ( Vimentin -/- mice). We identified distinct gene expression patter...

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Literature Corpus work: 4e8c4bb8-2436-5829-a339-47ced01564a2
DOI: 10.1101/2020.06.08.141309

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