Article

Oleic acid Induces Tissue Resident FoxP3 Regulatory T cell Lineage Stability and Suppressive Functions

2020-04-15

Abstract excerpt

<h4>ABSTRACT</h4> FoxP3 positive regulatory T cells (T regs ) rely on fatty acid β-oxidation (FAO)-driven OXPHOS for differentiation and function. Recent data have demonstrated a role for T regs in the maintenance of tissue homeostasis with tissue-resident T regs possessing tissue-specific transcriptomes. However, specific signals that establish these tissue-resident T regs programs are largely unknown. As T...

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Literature Corpus work: 6877d106-5982-55f9-8a3e-0d61b71b0bf2
DOI: 10.1101/2020.04.14.041525

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