Article

Quantitative analysis and genome-scale modeling of human CD4 <sup>+</sup> T-cell differentiation reveals subset-specific regulation of glycosphingolipid pathways

2021-01-31

Abstract excerpt

<h4>ABSTRACT</h4> T-cells are sentinels of adaptive cell-mediated immune responses. T-cell activation, proliferation and differentiation involves metabolic reprogramming involving the interplay of genes, proteins and metabolites. Here, we aim to understand the metabolic pathways involved in the activation and functional differentiation of human CD4 + T-cell subsets (Th1, Th2, Th17 and iTregs). We combined genome...

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Literature Corpus work: adb67bc2-7c80-5df4-b9b9-f2f414ab437a
DOI: 10.1101/2021.01.29.428853

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Quantitative analysis and genome-scale modeling of human CD4 <sup>+</sup> T-cell differentiation reveals subset-specific regulation of glycosphingolipid pathwaysDOI 10.1101/2021.01.29.428853Read

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