Article

Rapid adipose tissue expansion triggers proliferation of memory adipose tissue T cells and accumulation of novel T helper 2 (Th2) regulatory cells

2025-10-23

Abstract excerpt

<h4>ABSTRACT</h4> Obesity generates a pro-inflammatory state contributing to immune dysregulation and metabolic disease. In response to overnutrition, adipose tissue immune cells undergo dynamic changes featuring a shift from a type 2 anti-inflammatory phenotype in lean adipose tissue to a pro-inflammatory phenotype in obese adipose tissue, contributing to obesity associated adipose tissue inflammation featuring...

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Literature Corpus work: 20e815d8-b874-5dd1-af1b-45f85cbc0cda
DOI: 10.1101/2025.10.22.683711

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