Article

Oxidized phospholipid oxPAPC induces a Th1-like phenotype in regulatory T cells and inhibits their protective function in atherosclerosis

2023-02-11

Abstract excerpt

<h4>Background</h4> Regulatory T cells (T regs ) are protective in atherosclerosis but reduced during disease progression due to cell death and loss of stability. However, the mechanisms of T reg dysfunction remain unknown. Oxidized phospholipids (oxPLs) are abundant in atherosclerosis and can activate innate immune cells, but there is limited information regarding their impact on T cells. Given T reg loss dur...

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Literature Corpus work: bc723135-d27b-52cf-b842-0681877b2030
DOI: 10.1101/2023.02.08.527689

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Oxidized phospholipid oxPAPC induces a Th1-like phenotype in regulatory T cells and inhibits their protective function in atherosclerosisDOI 10.1101/2023.02.08.527689Read

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