Article

CD36 is a metabolic checkpoint for Th2 cell tissue residency during allergic airway inflammation

2025-09-20

Abstract excerpt

The prevalence of allergic diseases, including asthma, continues to rise in industrialized societies, yet the mechanisms sustaining pathogenic T helper 2 (Th2) responses remain incompletely understood. Here, we show that patients with allergic asthma exhibit elevated lipophilic volatile organic compounds in exhaled air and altered fatty acid–metabolism gene expression in sputum-derived Th2 cells. Using a mouse mod...

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Literature Corpus work: 5e564cdc-32ed-5102-b63c-b4c3bca645f8
DOI: 10.1101/2025.09.17.676489

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